Found 10 matching trials
Pilot Study of Pulmozyme (rhDNase) in Patients With Head and Neck Cancers Treated With Radiation Therapy + Chemotherapy
EARLY_PHASE1RATIONALE: Nebulized dornase alfa inhalation solution may decrease the thic...
Location
Robert H. Lurie Comprehensive Cancer Center at Northwestern University
Dornase Alpha Versus Hypertonic Saline for Lung Atelectasis in Non-Cystic Fibrosis Patients
NADespite the lack of trials proving the efficacy of DNase in non cystic fibr...
Location
Presbyterian Hospital
A Study of Pulmozyme® (Dornase Alpha) in 3- to 5-Year-Old Patients With Cystic Fibrosis
PHASE4This was a Phase IV, multicenter, randomized, double-blind, placebo-control...
Location
Multiple Locations
Dornase Alfa Therapy for Ventilator Associated Lung Infections in the Neonatal Intensive Care Unit (NICU)
PHASE4To evaluate the effect of Dornase alfa on preterm and late preterm neonates...
Location
Georgetown University Hospital NICU
Symptom Based Performance of Airway Clearance After Starting Highly Effective Modulators for Cystic Fibrosis (SPACE-CF)
NACystic Fibrosis (CF) is an autosomal recessive disease cause by a mutation ...
Location
University of Missouri Hospital and Clinics
Effectiveness of Pulmozyme in Infants With Cystic Fibrosis
PHASE2This is a study to find out whether Pulmozyme is effective for clearing muc...
Location
Nationwide Children's Hospital
Impact of Nebulized Dornase Alpha on Mechanically Ventilated Patients
NAThe investigators hypothesized that dornase alpha, administered twice a day...
Location
University of Medicine and Dentistry of New Jersey
Efficacy and Safety of Tigerase® vs. Pulmozyme® in Patients With Cystic Fibrosis
PHASE3It is a multicenter, open-label, randomized, parallel-group study of the ef...
Location
Regional Clinical Hospital
Dornase Alfa for ARDS in Patients With Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)
PHASE3This study is designed to evaluate a potential mechanism by which a hyperac...
Location
University of Missouri Hospital and Clinics
Dornase Alfa Administered to Patients With COVID-19 (DACOVID)
N/AMechanically ventilated patients with coronavirus disease 2019 (COVID-19) h...
Location
Feinstein Insitute for Medical Research at Northwell Health